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Author:   Arpad Szallasi
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2010 ed.
Volume:   617
Dimensions:   Width: 17.80cm , Height: 3.60cm , Length: 25.40cm
Weight:   1.405kg
ISBN:  

9781603273220

ISBN 10:   1603273220
Pages:   560
Publication Date:   25 March 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Alternatives to Mammalian Pain Models 1: Use of C. elegans for the Study of Volatile Anesthetics.- Alternatives to Mammalian Pain Models 2: Using Drosophila to Identify Novel Genes Involved in Nociception.- Animal Models of Acute Surgical Pain.- Animal Models of Acute and Chronic Inflammatory and Nociceptive Pain.- Noxious Heat Threshold Measured with Slowly Increasing Temperatures: Novel Rat Thermal Hyperalgesia Models.- Locomotor Activity in a Novel Environment as a Test of Inflammatory Pain in Rats.- Rationale and Methods for Assessment of Pain-Depressed Behavior in Preclinical Assays of Pain and Analgesia.- Animal Models of Orofacial Pain.- Migraine Models.- Experimental Models of Visceral Pain.- Human Correlates of Animal Models of Chronic Pain.- Human Experimental Pain Models 1: The Ultraviolet Light UV-B Pain Model.- Human Experimental Pain Models 2: The Cold Pressor Model.- Human Experimental Pain Models 3: Heat/Capsaicin Sensitization and Intradermal Capsaicin Models.- The Value of the Dental Impaction Pain Model in Drug Development.- Live Cell Imaging for Studying G Protein-Coupled Receptor Activation in Single Cells.- Recombinant Cell Lines Stably Expressing Functional Ion Channels.- Ion Channels in Analgesia Research.- Electrophysiological and Neurochemical Techniques to Investigate Sensory Neurons in Analgesia Research.- The Genetics of Pain and Analgesia in Laboratory Animals.- RT-PCR Analysis of Pain Genes: Use of Gel-Based RT-PCR for Studying Induced and Tissue-Enriched Gene Expression.- Gene-Based Approaches in the Study of Pathological Pain.- Linkage Analysis and Functional Evaluation of Inherited Clinical Pain Conditions.- Rat Bone Marrow Stromal Cells and Oligonucleotides in Pain Research.- Transplantation of Human Mesenchymal Stem Cells in the Studyof Neuropathic Pain.- Delivery of RNA Interference to Peripheral Neurons In Vivo Using Herpes Simplex Virus.- Combination of Cell Culture Assays and Knockout Mouse Analyses for the Study of Opioid Partial Agonism.- Assessing Potential Functionality of Catechol-O-methyltransferase (COMT) Polymorphisms Associated with Pain Sensitivity and Temporomandibular Joint Disorders.- Genetic Polymorphisms and Human Sensitivity to Opioid Analgesics.- Molecular Assays for Characterization of Alternatively Spliced Isoforms of the Mu Opioid Receptor (MOR).- Inhalational Anesthetic Photolabeling.- Measuring Membrane Protein Interactions Using Optical Biosensors.- Proteomics and Metabolomics and Their Application to Analgesia Research.- Preemptive Analgesia: Problems with Assessment of Clinical Significance.- Standardization of Pain Measurements in Clinical Trials.- Procedural Sedation and Analgesia Research.- Non-invasive Transcranial Direct Current Stimulation for the Study and Treatment of Neuropathic Pain.- Pain Imaging in the Emerging Era of Molecular Medicine.- Current and Emerging Pharmacologic Therapies for Pain and Challenges Which Still Lay Ahead.

Reviews

From the reviews: This book is a collection of methods used to study pain physiology, pharmacology, and genetics described by researchers in the field. ! intended to assist basic scientists and clinicians who are interested in the molecular aspects of pain research. ! This is a most unique book in the field of pain medicine. ! The book imparts a lot of information about the future of pain medicine and is a must read for pain physicians who want to be at their best when managing their patients. (Tariq M. Malik, Doody's Review Service, August, 2010)

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