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Author:   Robert Becker ,  Ezio Giacobini
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Edition:   1997 ed.
Dimensions:   Width: 15.50cm , Height: 3.40cm , Length: 23.50cm
Weight:   2.330kg
ISBN:  

9780817638795

ISBN 10:   0817638792
Pages:   614
Publication Date:   01 December 1996
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

I. Pathological Basis of Therapy in Alzheimer’s Disease.- Criteria for the Diagnosis of Alzheimer’s Disease.- Neuropathology Of Alzheimer’s Disease.- Processing of Amyloid, Cytoskeletal Damage and Apolipoproteins.- Cell Death: Excitotoxins, Apoptosis And Hypometabolism.- Neurotrophins, Growth Factors and Neuroprotectors.- Animal Models.- II. The Cholinergic System in Brain.- Treatment of Alzheimer Disease.- Cholinesterase Inhibitors in Alzheimer Disease Treatment.- III. Nicotinic and Muscarinic Cholinergic Agonists.- Nicotinic Agonists.- Muscarinic Agonists and Antagonists.- The Potential of Antioxidant Therapy.- The Potential for Anti-Inflammatory Therapy.- IV. Development of New Therapies in Alzheimer Disease.- Design of Clinical Trials.- Advances in Assessment.- SPECT and PET.- Potential Markers of Disease Progression and Drug Efficacy in Alzheimer’s Disease.- Treatment of Behavioral and Psychosocial Disturbances.- V. Social Issue in Alzheimer Disease.- Legal and Ethical Issues.- Socio-Economic As pects of Alzheimer Disease Treatment.- International Harmonization of Drug Guidelines.- Research Priorities in Alzheimer Disease Treatment — An International Perspective.- Author Index.

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