Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases

Author:   Namita Agrawal
Publisher:   Springer Verlag, Singapore
Edition:   2024 ed.
ISBN:  

9789819742875


Pages:   438
Publication Date:   13 August 2024
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Altered Metabolism: A Major Contributor of Comorbidities in Neurodegenerative Diseases


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Overview

This book presents a systematic and extensive understanding about metabolic alterations affecting multiple aspects of different neurodegenerative diseases (NDDs), such as Alzheimer’s, Parkinson’s, Huntington’s disease, SCAs, SBMA, DRPLA, ALS, Freidrich Ataxia etc. The book also illustrates  cellular and molecular mechanisms behind the key  neurodegenerative diseases and further expands on concept of unique and developing biomarkers associated with the onset and progression of NDDs. Additionally, it elaborates on the concept of latest imaging tools to monitor state of NDDs and accordingly develop therapeutic approaches entailing phytochemicals in the management of metabolic alterations associated with NDDs that ultimately suppresses course of devastating NDDs. The book aids to improve the overall understanding about the NDD and involvement of metabolic disorder as a major factor for indisposition of the disease. Therefore, suggesting that targetting metabolic variations by phytochemicals can combat NDD related symptoms for the betterment of impacted patients. While introducing cellular and molecular mechanisms and the treatment regimen under the umbrella of metabolism in several NDDs, the book covers major aspects of understanding the metabolic basis of NDDs, its implications, and treatment. This will inflate the readers' understanding about this particular area and guide those working in this domain, be it a researcher or clinicians,to choose or design effective therapeutic strategies to curb metabolic alterations linked with these disorders. This book will not only contribute towards improving the overall state of the challenged individuals but will also bring new hope towards improving the quality of lives of affected patients.

Full Product Details

Author:   Namita Agrawal
Publisher:   Springer Verlag, Singapore
Imprint:   Springer Nature
Edition:   2024 ed.
ISBN:  

9789819742875


ISBN 10:   9819742870
Pages:   438
Publication Date:   13 August 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Chapter 1: An Overview of Neurodegenerative Disorders.- Chapter 2: Mechanism underlying major neurodegenerative disorders.- Chapter 3: Involvement of metabolic paradigm in progression of neurodegenerative diseases.- Chapter 4: Glial cell metabolism and neurodegenerative diseases: The current perspective.- Chapter 5: Altered glucose homeostasis in neurological disorders.- Chapter 6: Lipid Metabolism: Key Determinant in Neurodegenerative Diseases.- Chapter 7 - Dysregulated peripheral metabolism in neurodegenerative disorders.- Chapter 8- Protein Metabolism: Critical factors implicated in neurodegenerative diseases.- Chapter 9 - Altered RNA metabolism in neurodegenerative disorders.- Chapter 10: Unveiling RNA dysfunction: A key player in neurodegeneration.- Chapter 11: Emerging Relationship between the Gut Microbiota and Neurodegenerative Disorders.- Chapter 12- Signaling Pathways in Neurodegenerative diseases.- Chapter 13: An overview of imaging techniques for diagnosis of debilitating neurodegenerative diseases.- Chapter 14: Novel Metabolic Biomarkers and Therapeutic Strategies in Neurodegenerative Diseases.- Chapter 15: Phytochemicals: Promising alternatives for metabolic regulation in neurodegenerative diseases.

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Author Information

Namita Agrawal is currently a Professor at the Department of Zoology, University of Delhi, India. Prof. Agrawal has been addressing numerous questions related to debilitating neurodegenerative diseases for past 25 years. She started working on neurodegenerative diseases at the  Department of Development and Cell Biology, University of California, Irvine, USA. Her research group at University of Delhi is  trying to comprehend the mechanistic basis of neurodegenerative diseases and its cure  by using phytochemicals. Additionally, her research interests also include understanding of various aspects involved in Cancer and  nanomaterials.Prof. Agrawal has published research papers in peer-reviewed journals like Science, PNAS, Journal of Cell Biology, Development, Developmental Biology, Nature Scientific Reports, PLOS One, J. of Huntington’s disease etc. She has recently edited and wrote several chapters in a book published by Springer entitled “Toxicology of Nanoparticles: Insights from Drosophila”. Additionally, she frequently writes chapters in the books related to neurodegenerative diseases. In addition to her dedication towards research, Dr. Agrawal has almost 15 years of experience in teaching Genetics, Cytogenetics and Developmental Biology to post-graduate students at the Department of Zoology, University of Delhi, India.  

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