Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo
Author:   David Raeburn ,  Mark A. Giembycz
Publisher:   Birkhauser Verlag AG
Edition:   Softcover reprint of the original 1st ed. 1996
ISBN:  

9783034898638


Pages:   300
Publication Date:   01 October 2011
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Airways Smooth Muscle: Modelling the Asthmatic Response In Vivo


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Overview

Building on the existing titles in the ""Airways Smooth Muscle"" sub-series, the sixth volume explores physiological and pharmacological processes in the lung in vivo. The various animal models available for studying the bronchospasm and inflammation associated with human asthma are thoroughly reviewed by internationally recognised scientists. Specific chapters focus on the problems of administering drugs to animal airways, the mechanics of assessing lung function in the models, and describe in detail the species used, from rodents to primates. The use of genetically altered animals, an area of particular interest to molecular biologists, is also considered in depth. This up-to-date and extensively referenced work will prove invaluable to pharmacologists, physiologists and other biological scientists at all levels in academia and in the pharmaceutical industry.

Full Product Details

Author:   David Raeburn ,  Mark A. Giembycz
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   Softcover reprint of the original 1st ed. 1996
Dimensions:   Width: 17.00cm , Height: 1.50cm , Length: 24.40cm
Weight:   0.508kg
ISBN:  

9783034898638


ISBN 10:   3034898630
Pages:   300
Publication Date:   01 October 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Measurement of Airways Smooth Muscle Responsiveness in Animals.- 2. Methods of Drug Administration to the Lung in Animals.- 3. PAF and Antigen-Induced Bronchial Hyperreactivity in Guinea Pigs.- 4. Antigen-Induced Bronchial Hyperreactivity in Rats.- 5. Ozone-Induced Bronchial Hyperreactivity.- 6. Virus-Induced Bronchial Hyperreactivity.- 7. The Rabbit Model of Asthma and the Late Asthmatic Response.- 8. The Sheep as a Model of the Late Asthmatic Response.- 9. Primate Models of Asthma.- 10. The Sensitized Pig Model of Asthma.- 11. Transgenic Animals and the Modelling of Asthma.

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