Overview

The state of health care is reflected by perinatal and neonatal morbidity and mortality as well as by the frequencies of long-term neurologic and developmental disorders. Many factors, some without immediately rec­ ognizable significance to childbearing and many still unknown, undoubt­ edly contribute beneficially or adversely to the outcome of pregnancy. Knowledge concerning the impact of such factors on the fetus and sur­ viving infant is critical. Confounding analyses of pregnancy outcome, especially these past two or three decades, are the effects of newly un­ dertaken invasive or inactive therapeutic approaches coupled with the advent of high technology. Many innovations have been introduced with­ out serious efforts to evaluate their impact prospectively and objectively. The consequences of therapeutic misadventures characterized the past; it seems they have been replaced to a degree by some of the complications of applied technology. Examples abound: after overuse of oxygen was recognized to cause retrolental fibroplasia, its restriction led to an in­ crease in both neonatal death rates and neurologic damage in surviving infants. Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dos­ age, occasionally resulted in kernicterus. Prophylactic sulfonamide use had a similar end result. More recent is the observation of bronchopul­ monary dysplasia as a complication of respirator therapy for hyaline membrane disease.

Full Product Details

Author:   E. Friedman ,  L. Gluck ,  Aubrey Milunsky
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   Softcover reprint of the original 1st ed. 1986
Dimensions:   Width: 15.20cm , Height: 1.60cm , Length: 22.90cm
Weight:   0.447kg
ISBN:  

9781461594703

ISBN 10:   1461594707
Pages:   298
Publication Date:   12 February 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1 Nutritional Supplementation of the Growth-Retarded Fetus: Rationale, Theoretical Considerations, and in Vivo Studies.- 1. Introduction.- 2. Rationale for Considering Nutritional Therapy.- 3. Theoretical Considerations in Providing Nutritional Supplementation.- 4. Fetal Nutritional Supplementation: Human and Animal Studies.- 5. Conclusions.- References.- 2 Transplacental Toxicity of Environmental Chemicals: Environmental Causes and Correlates of Spontaneous Abortions, Malformations, and Childhood Cancer.- 1. Introduction.- 2. Environmental Chemicals and Spontaneous Abortions.- 3. Environmental Chemicals and Malformations.- 4. Parental Occupation and Cancer in the Offspring.- 5. Conclusions.- References.- 3 Neonatal Polycythemia and Hyperviscosity.- 1. Introduction.- 2. Definition.- 3. Incidence.- 4. Viscosity.- 5. Hemodynamic Changes in Polycythemic and Hyperviscous States.- 6. Etiology.- 7. Clinical Symptoms.- 8. Management.- References.- 4 Maternal Psychoactive Substance Use and Its Effect on the Neonate.- 1. Introduction.- 2. Cigarette Smoking.- 3. Caffeine.- 4. Alcohol.- 5. Marijuana Use.- 6. Opiate Use.- 7. Amphetamines.- 8. Cocaine.- 9. Barbiturates.- 10. Phencyclidine.- 11. Diazepam.- 12. Summary.- References.- 5 Effect of Maternally Administered Drugs on the Fetus and Newborn.- 1. Introduction.- 2. Background Information.- 3. Methods of Pain Relief.- 4. Anesthesia and the Compromised Fetus.- 5. Relationship of Obstetric Anesthesia to Long-Term Neonatal Effects.- References.- 6 Chlamydial Infection.- 1. Introduction.- 2. Organism.- 3. Epidemiology.- 4. Perinatal Infections.- 5. Neonatal Infections.- 6. Diagnosis.- 7. Therapy.- References.

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