Overview

Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future.

Full Product Details

Author:   Frederick W. Alt (Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) ,  Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) ,  Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA) ,  Frederick W. Alt (Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   89th edition
Volume:   115
Weight:   0.620kg
ISBN:  

9780123942999

ISBN 10:   0123942993
Pages:   258
Publication Date:   12 July 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The Immunobiology of IL-27 Aisling O’Hara Hall, Jonathan S. Silver, and Christopher A. Hunter Autoimmune Arthritis: The Interface between the Immune System and Joints Noriko Komatsu and Hiroshi Takayanagi Immunological Tolerance during Fetal Development: From Mouse to Man Jeff E. Mold and Joseph M. McCune Mapping Lupus Susceptibility Genes in the NZM2410 Mouse Model Laurence Morel Functional Heterogeneity in the Basophil Cell Lineage Mark C. Siracusa, Elia D. Tait Wojno & David Artis An Emerging Role of RNA-Binding Proteins as Multifunctional Regulators of Lymphocyte Development and Function Martin Turner and Daniel Hodson Active and Passive Anti-cytokine Immune Therapies Current Status and Development Helene Le Buanec, Armand Bensussan, Martine Bagot, Robert C. Gallo, Daniel Zagury

Reviews

The series which all immunologists need. -- The Pharmaceutical Journal <br> Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions. -- Science <br> Deserves a permanent place in biomedical libraries as an aid in research and in teaching. -- Journal of Immunological Methods

Author Information

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.

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