Overview

Blood stem cell transplantation has become an established therapeutic option in the treatment of malignant diseases. At the same time molecular therapeutic approaches (i.e. gene therapy) are promising alternatives to the classical treatment of cancer. The proceedings give an overview of the biology of hematopoietic progenitor cells, peripheral stem cell transplantation in patients with hematological malignancies, recent developments in molecular diagnosis and gene therapeutic concepts, and show that successful future developments require cooperative research connecting basic science with clinical application.

Full Product Details

Author:   Rainer Haas ,  Ralf Kronenwett ,  Georg Sczakiel
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1998
Volume:   144
Dimensions:   Width: 15.50cm , Height: 0.80cm , Length: 23.50cm
Weight:   0.260kg
ISBN:  

9783642468384

ISBN 10:   3642468381
Pages:   150
Publication Date:   04 April 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Mobilization and Selection of CD34+ Cells.- Autologous Stem Cell Transplantation for Chronic Myeloid Leukemia.- Autologous Stem Cell Transplantation in Aggressive Non-Hodgkin’s Lymphoma.- Peripheral Blood Progenitor Cell Transplantation in Multiple Myeloma Following High-Dose Melphalan-Based Therapy.- Molecular Monitoring of Residual Disease in Chronic Myelogenous Leukemia Patients After Therapy.- Delineation of Genomic Regions in Chromosome Band 7q22 Commonly Deleted in Myeloid Leukemias.- Molecular Cytogenetic Analysis of Low-Grade B-Cell Neoplasias: a Comparative Genomic Hybridization Study.- Applications of Gene Transfer in Hematologic Malignancy.- Dendritic Cells for Somatic Gene Therapy.- Construction of Immunogenic Tumor Cell Surfaces by Somatic Gene Transfer.- Adeno-associated Virus Type 2 Vector for Transduction of Hematopoietic Cells.- Protection of Hematopoietic Stem Cells from Chemotherapy-Induced Toxicity by Multidrug-Resistance 1 Gene Transfer.- Regulated Gene Expression After Retroviral Vector-Mediated Delivery of Cancer-Relevant Therapeutic Genes.- Specific bcr-abl-Directed Antisense Nucleic Acids and Ribozymes: A Tool for the Treatment of Chronic Myelogenous Leukemia?.- The Use of Ribozymes in Gene Therapy Approaches to AIDS.

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