Overview

Since human prolactin was isolated and characterized 13 years ago, the study of the control of prolactin secretion has been intensive. Hyperprolactinaemia is the most commonly identifiable hypothal- amic pituitary disorder1,2. The dominant inhibitory nature of hypo- thalamic control of prolactin secretion may be the reason that hyperprolactinaemia is such a common condition. During the PClst decade two separate therapeutic approaches to the management of hyperprolactinaemia have been introduced: transsphenoidal selec- tive pituitary microsurgery and medical therapy to suppress prolactin secretion with orally active long-acting dopamine agonist drugs. Small prolactin-secreting tumours are treated extremely satisfactorily both with medical and with surgical therapy, both in terms of lower- ing serum prolactin levels to normal and in restoring gonadal func- tion. However, for the larger tumours, either where the tumour is invasive or the pretreatment serum prolactin level is greater than 1 250ngml- the results of surgery are poor in terms of restoring to normal circulating prolactin levels and gonadal functionJ-s. We now discuss the medical management of hyperprolactinaemia, potential problems during pregnancy and the management of large prolactin- secreting pituitary tumours.

Full Product Details

Author:   R. Rolland
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of the original 1st ed. 1984
Dimensions:   Width: 15.50cm , Height: 0.60cm , Length: 23.50cm
Weight:   0.195kg
ISBN:  

9789401159326

ISBN 10:   9401159327
Pages:   117
Publication Date:   28 January 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1 Pre-treatment evaluation of ovarian infertility.- 2 Hyperprolactinaemic infertility: some considerations on medical management.- 3 Lisuride — a new drug for treatment of hyperprolactinaemic disorders.- 4 Benefits and risks of hormonal contraception — interpretation.- 5 Towards safer oral contraception.- 6 The influence of the triphasic pill and a desogestrel-containing combination pill on some physical, biochemical and hormonal parameters: a preliminary report.- 7 Clinical comparison between a monophasic preparation and a triphasic preparation.- 8 Comparative study of lipid metabolism and endocrine function in women receiving levonorgestrel- and desogestrel-containing oral contraceptives.- 9 Androgenic properties of progestogens used in oral contraceptives.- 10 Effect of oral contraceptives upon serum lipoprotein pattern in healthy women.- 11 Carbohydrate metabolism alterations with monophasic, sequential and triphasic oral contraceptives containing ethinyloestradiol plus levonogestrel or desogestrel.

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