The Molecular Immunology of Complex Carbohydrates

Author:   Albert M. Wu ,  L. Garry Adams
Publisher:   Springer Science+Business Media
Edition:   1988 ed.
Volume:   228
ISBN:  

9780306428180


Pages:   868
Publication Date:   01 July 1988
Format:   Hardback
Availability:   Out of stock   Availability explained
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The Molecular Immunology of Complex Carbohydrates


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Author:   Albert M. Wu ,  L. Garry Adams
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   1988 ed.
Volume:   228
Weight:   2.460kg
ISBN:  

9780306428180


ISBN 10:   0306428180
Pages:   868
Publication Date:   01 July 1988
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

I. Antibody Specificity, Epitope and Lectinology.- I-1 Antibody Combining Sites: How Much of the Antibody Repertoire are We Seeing? How does it Influence Our Understanding of the Structural and Genetic Basis of Antibody Complimentarity?.- I-2 Sialic Acids as Antigenic Determinants of Complex Carbohydrates.- I-3 Blood Group Active Haptens in Urine and Faeces.- I-4 The Separation of Immunocyte Subpopulations by Use of Various Lectins.- I-5 Mannose-binding Proteins of Animal Origin.- I-6 Sialic Acid and N-Acetylgalactosamine Specific Bacterial Lectins of Enterotoxigenic Escherichia coli (ETEC).- I-7 Interaction of Viruses, Bacteria and Bacterial Toxins with Host Cell Surface Glycolipids. Aspects on Receptor Identification and Dissection of Binding Epitopes.- I-8 Membrane Glycoproteins and Plant and Animal Proteins with Lectin or Lectin-like Properties.- I-9 Differential Binding Properties of GalNAc and/or Gal Specific Lectins.- II. Complex Carbohydrates as Antigens.- II-l Antigenic Properties of Human Erythrocyte Glycophorins.- II-2 Carbohydrate Structures as ONCO-Developmental Antigens and Components of Receptor Systems.- II-3 Chemistry of Human Erythrocyte Polylactosamine Glycopeptides (Erythroglycans) as Related to ABH Blood Group Anitgenic Determinants.- II-4 Blood Group Antigens and the Enzymes Involved in their Synthesis: Past and Present (Abstract).- II-5 Structural Concepts of the Human Blood Group A, Lea, Leb, I, and i Active Glycoproteins Purified from Human Ovarian Cyst Fluid.- II-6 Biochemistry and Lectin Binding Properties of Mammalian Salivary Mucous Glycoproteins.- II-7 New Trends in Ganglioside Chemistry.- II-8 Structural Aspects of Blood Group Glycosphingolipids in the Gastrointestinal Tract.- II-9 Chemically Modified Capsular Polysaccharides as Vaccines.-II-10 Structural and Immunochemical Aspects of Brucella Abortus Endotoxins.- II-11 Chemical and Immunochemical Studies on Lipopolysaccharides of Coxiella Burnetii Phase I and Phase II.- II-12 Structural Comparisions of Streptococcus pneumonaiae Specific Polysaccharides of Group 9 (9N, 9V, 9L, 9A) Related to the Choice of Vaccine Components (Abstract).- II-13 Elucidation and Comparison of the Chemical Structures of the Specific Capsular Polysaccharides of Streptococcus pneumoniae Groups 11 (11F, 11B, 11C, 11A) (Abstract).- II-14 Application of Two Dimensional NMR Methods to the Structural Elucidation of Complex Polysaccharide Antigens. The Structure of the Capsular Polysaccharide of Streptococcus pneumoniae Type 22F (Abstract).- II-15 Structural and Immunochemical Investigations on Snail Galactans (Abstract).- III. Glycoconjugates as Cancer/or Tumor Antigens.- III-l Tumor-Associated Blood Group Antigen Expressions and Immunoglobulins Associated with Tumors.- III-2 The Chemical Basis for Expression of the Sialyl-Lea Antigen.- III-3 Glycoconjugates and Tumor Metastasis.- III-4 Glycolipids and Glycoproteins in Plasma Membrane of Hepatocellular Cancer.- III-5 Cancer-Associated Carbohydrate Antigens in Mucins (Abstract).- III-6 N-Glycolylneuraminic Acid-Containing Gangliosides as a Tumor Associated Antigen in Human: Expression of Hunganutziu-Deicher Antigen Active Gangliosides on Human Colon Carcinoma and Melanoma Tissues (Abstract).- IV. Structural Analysis of Hapten Moiety of Complex Carbohydrate Antigens.- IV-1 Structural Elucidation of Complex Carbohydrates.- IV-2 Analysis of Complex Carbohydrate Primary and Secondary Structure Via Two-Dimensional Proton Nuclear Magnetic Resonance Spectroscopy.- IV-3 Structural Studies on the Carbohydrate Chains of Glycoproteins (Abstract).- IV-4 The Use of Enzymes for Structural Determination of Complex Carbohydrates.- IV-5 Mass Spectrometry of Hexosamine Containing Oligosaccharides as Permethylated N-Trifluoroacetyl Derivatives.- IV-6 Immunochemical Analysis of Lipopolysaccharides with 2-D Gel Electrophoresis and Monoclonal Antibodies (Abstract).- A-1 A Guide for Carbohydrate Specificities of Lectins.- Contributors.

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Dr. Wu has been studying on lectin glycan interactions for more than 35 years, especially the recognition factors of lectins. He is the senior editor of the Molecular Immunology of Complex Carbohydrates 1 and 2 (Adv. Exp. Med. Biol. 228 and 491). Lectin recognition index is his ongoing project.

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