Overview

In a bid to develop synthetic molecules and materials that are capable of mimicking biological recognition and function, intensive research in the fields of synthetic receptor technologies, smart materials, synthetic biology and smart indicators has been under way for the past 20-30 years. The development of synthetic receptors continues to grow rapidly. Novel molecular architectures, with ever improving selective binding properties are constantly being described, and in some cases providing much-needed physical insights into the nature of non-covalent interactions and molecular recognition. Such receptor systems are finding increasingly esoteric applications and this book captures the key developments at the synthetic receptor/biology/detection science interface. The editor has extensive experience in applying smart materials and synthetic receptors to the development of biosensors. Reddy has developed smart, permselective and biocompatible molecularly imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. Chapters demonstrate how growing disciplines such as biomimetics, synthetic receptor technologies, pattern recognition and nanotechnology are being used to develop new smart materials for diagnostic sensor and biosensor applications. Postgraduate students and researchers in academia and industry will benefit from this resourceful handbook.

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9781849735933

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Reviews

This is a very good, interesting book and one that should be on your desk if you are working in the area of materials for detection science. I liked the fact that for this book the RSC has published some figures in colour. This is needed with the complexity of some of the diagrams.. The book consists of seven chapters taking the reader from biomimicry and materials to biomimetic materials and surface detection. ...a very good book and one that in today's high price market is worth the money. -- Peter Myers Chromatographia 78:299-300 I must admit that I am not a fan of multi-authored books consisting of one editing author and the chapters authored by a wide variety of people. Only on the rare occasion have I found that there is a flow from one chapter to another. I am pleased to say that this book is, however, one that does work and there is a logical flow from one chapter to another. This may be because the majority of the authors are from the University of Surrey and the editing author has ensured that they have written to a given brief. This is a very good, interesting book and one that should be on your desk if you are working in the area of materials for detection science. I liked the fact that for this book the RSC has published some figures in colour. This is needed with the complexity of some of the diagrams; even so some diagrams are just too complex and small that they do not work on the printed page. The book consists of seven chapters taking the reader from biomimicry and materials to biomimetic materials and surface detection. These are two very good opening chapters and form a very good base for the rest of the book. The third chapter goes into more detail and considers hydrogel-based molecularly imprinted polymers. An interesting chapter, but I always feel that the benefit of MIPSs has always been overstated and we are still a long way from understanding the true nature of the cavities formed in the imprinted polymer and the true interactions that occur as a result of the cavities. But the authors do recognise these problems and do give a very good summary on the real challenges that have to be overcome in molecular imprinting. I do not suppose you can write a book today on detection without including a chapter on nanoparticles and this book is no exception. Chapter 4 deals with nanoparticle technologies. In comparison to the other chapters it is quite short and I would have expected far more from this very active area. In particular the author in his conclusion states how we will see more uses of nanoparticles coupled to miniaturisation technologies. These are with us now and I was left wanting to know more about what targets have been addressed and exactly what is happening. For me Chapter 7 was the highlight of the book, but maybe this should be expected as it was written by the editor. The subject of this chapter, Smart Indicator Technologies , has to be one of the major growth areas of the future. We really have moved on a lot since universal indicator days!! Chapter 8 does follow-on very nicely with the development of ion-selective electrodes. The author talks mainly about the functionalization of calixpyrrole through extending the arm groups so as to impart the desired selectivity to the electrode. This is his base model but shows what may be possible with some new macrocylic molecules. If there is a weak chapter it is the last on recognition techniques in the development of the electronic tongue. There are eight pages of tables in this chapter. In a book of this nature I want descriptions and explanations, not tables. But do not let this put you off what is a very good book and one that in today's high price market is worth the money. -- Peter Myers Chromatographia (2015) 78:299-300

Author Information

Dr. Sub Reddy (C.Chem. MRSC) obtained his first class degree in Chemistry from the University of Manchester. He received his Ph.D. in Membrane-based Electrochemical Biosensing from the same University (1996). His post-doctoral research interests have included the development of quartz crystal-based biosensors, operating in the liquid phase (University of Wales, Bangor; 1994-1997) and the development of application-specific odour sensors (UMIST, Manchester; 1997-1998).

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