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OverviewAdvanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics presents the latest emerging technologies in spectroscopy and advances in established spectroscopic methods. The book presents a guide to research methods in biomolecular spectroscopy, providing comprehensive coverage of developments in the spectroscopic techniques used to study protein structure and dynamics. Seventeen chapters from leading researchers cover key aspects of spectroscopic methods, with each chapter covering structure, folding, and dynamics. This title will help researchers keep up-to-date on the latest novel methods and advances in established methods. Full Product DetailsAuthor: Prakash Saudagar (Assistant Professor at the Department of Biochemistry, National Institute of Technology Warangal, India) , Timir Tripathi (Molecular and Structural Biophysics Laboratory, Department of Zoology, School of Life Sciences, North-Eastern Hill University, Shillong, Meghalaya, India)Publisher: Elsevier Science & Technology Imprint: Academic Press Inc Weight: 0.860kg ISBN: 9780323991278ISBN 10: 0323991270 Pages: 558 Publication Date: 29 September 2022 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand ![]() We will order this item for you from a manufactured on demand supplier. Table of Contents1. Fundamentals of spectroscopy for biomolecular structure and dynamics 2. Fluorescence-based techniques to assess biomolecular structure and dynamics 3. Structural analysis of biomacromolecules using circular dichroism spectroscopy 4. Nuclear magnetic resonance spectroscopy for protein structure, folding, and dynamics 5. Advanced NMR spectroscopy methods to study protein structure and dynamics 6. Applications of infrared spectroscopy to study proteins 7. Raman spectroscopy to study biomolecules, their structures, and dynamics 8. Spectroscopic investigation of biomolecular dynamics using light scattering methods 9. Protein footprinting by mass spectrometry: H/D exchange, specific amino acid labeling, and fast photochemical oxidation of proteins 10. Small angle scattering techniques for biomolecular structure and dynamics 11. Advances in X-ray crystallography methods to study structural dynamics of macromolecules 12. Spectroscopic methods to study protein folding kinetics: methodology, data analysis, and interpretation 13. Spectroscopic methods to study the thermodynamics of biomolecular interactions 14. Spectroscopic methods to detect and analyze protein oligomerization, aggregation, and fibrillation 15. Multimodal spectroscopic methods for the analysis of carbohydrates 16. Integration of spectroscopic and computational data to analyze protein structure, function, folding, and dynamics 17. Advance data handling tools for easy, fast, and accurate interpretation of spectroscopic dataReviewsAuthor InformationDr. Prakash Saudagar is an active researcher and a sterling classroom teacher, currently working as an Assistant Professor at the Department of Biochemistry, National Institute of Technology Warangal, India. He obtained his Ph.D. degree from the Indian Institute of Technology, Guwahati, India, in 2013. His research has immensely contributed to exploring potential drug target proteins and inhibitors. His research interests include molecular and biochemical parasitology, infectious disease, and protein biochemistry. He has a strong command over computational techniques and in-vitro techniques used to study proteins. He has published more than 40 research articles in reputed journals like the International Journal of Biological Molecules, FEBS, FEBS OpenBio, PLOS one, Scientific Reports, Biological Chemistry, Parasitology International, Molecular Simulation, etc., and book chapters in Elsevier and Springer to his name. He has been PI/Co-PI in research grants from SERB and DST. He has been awarded the B.S. Narasinga Rao award SBC, India (2011), Best presentation award, ICIDN, Nepal (2015), Young Faculty Award, VIF India (2016), and Young Scientist Award, Telangana Academy of Science (2018). He is an associate fellow of the Telangana Academy of Science (2018) and a life member of the Indian Science Congress and Society of Biological Chemists. He has guided several Ph.D. and M.Tech. students, postdoctoral fellows, project fellows, and trainees. He has many interdisciplinary collaborating partners in prestigious institutions in India and abroad. Prof. Timir Tripathi is a Professor of Molecular Biology in the Department of Zoology, School of Life Sciences, North-Eastern Hill University, Shillong, India. Earlier, he served as the Regional Director of Indira Gandhi National Open University, Kohima, Nagaland (2022-2023), where he contributed significantly to educational leadership, governance, and management. Before this, he was Senior Assistant Professor and Principal Investigator at the Department of Biochemistry, NEHU, Shillong (2009-2022). He holds a Ph.D. from Jawaharlal Nehru University, New Delhi, while working at the Central Drug Research Institute, Lucknow. He was a visiting faculty at ICGEB, New Delhi, India, and Khon Kaen University, Thailand. His research interests lie in the field of protein-substrate interaction and dynamics and understanding the roles of non-catalytic domains in regulating the catalytic activity of proteins. His primary focus is studying the conformational dynamics, interaction, and stabilization of the complexes formed by intrinsically disordered neuropathological protein aggregates, their properties of liquid-liquid phase separation, interaction, and roles in nucleocytoplasmic transport in neurodegenerative diseases. In addition, he is interested in analyzing the structural and functional characteristics of drug target proteins from the helminth liver fluke parasite Fasciola gigantica to identify new therapeutic strategies. He has received several national and international awards. He is an Associate Fellow of the Indian National Science Academy, New Delhi, and an elected member of the National Academy of Sciences, India, the Royal Society of Chemistry, and the Royal Society of Biology, UK. He has handled several research grants as a principal investigator from various national and international funding agencies. He has published over 100 research papers, reviews, commentaries, viewpoints, outlooks, and editorial articles in international journals, and has contributed several book chapters. He has edited six books and authored two textbooks for undergraduate and postgraduate students. Currently, he serves as the editor of the International Journal of Biological Macromolecules (Elsevier), senior editor of Critical Insights in Biophysics (Taylor & Francis), and is a member of the editorial boards of Scientific Reports and Acta Tropica. Tab Content 6Author Website:Countries AvailableAll regions |