Overview

The scope of the field of biotechnological processes is very wide, covering such processes as fermentations for production of high-valued specialist chemicals (e.g. pharmaceuticals), high-volume production of foods and feeds (e.g. yoghurt, cheese, beer), as well as biological waste treatment, handling solid (composting), liquid (activated sludge) and gaseous wastes (biofilters). Compared to other engineering disciplines, the introduction of modern optimization and control strategies is lagging behind. Two main reasons can be identified. First, the living organisms (or part thereof) that are central to these processes make the mathematical modeling of the processes a difficult task, and, since models are central to the development of control systems, the on-line control problem is also complex. The other difficulty stems from the absence, in most cases, of cheap and reliable instrumentation suited to real-time monitoring. In this book a number of advanced techniques is introduced to deal with these problems. In the first part modern on-line hardware sensors are discussed in detail (FIA, viable biomass measurement, membrane inlet mass spectrometry, flow cytometry, microcalorimetry). In the second part, novel model-based process diagnosis and control techniques are dealt with, including advances in bioprocess modeling and identification, data processing, software sensor design, and on-line control algorithms. The book is directed at engineers, researchers, and students in the field of process control and systems theory as applied to industrial biotechnological processes, as well as at bioengineers who have some background in control engineering and wish to increase their understanding of how advanced control theory applies to biological processes.

Full Product Details

Author:   J.F. van Impe ,  P.A. Vanrolleghem ,  D.M. Iserentant
Publisher:   Springer
Imprint:   Springer
Edition:   Softcover reprint of hardcover 1st ed. 1998
Dimensions:   Width: 15.50cm , Height: 2.40cm , Length: 23.50cm
Weight:   0.735kg
ISBN:  

9789048149544

ISBN 10:   9048149541
Pages:   464
Publication Date:   01 December 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

I Hardware Sensors.- 1 Flow Injection Analysis for On-line Monitoring of a Wastewater Treatment Plant.- 2 On-line Measurement of Viable Biomass.- 3 Membrane Inlet Mass Spectrometry for the Characterization and Monitoring of Biotechnological Processes.- 4 Flow Cytometry.- 5 Microcalorimetric Characterization of Bacterial Inocula.- II Model based Control.- 6 On-line Data Acquisition.- 7 Data Processing for System Identification.- 8 Error Diagnosis and Data Reconciliation Using Linear Conservation Relations.- 9 General Concepts of Bioprocess Modeling.- 10 Bioprocess Model Identification.- 11 Optimal Control of Fed-Batch Fermentation Processes.- 12 Monitoring and Adaptive Control of Bioprocesses.- 13 Optimal Adaptive Control of Fed-Batch Fermentation Processes.- 14 Predictive Control in Biotechnology using Fuzzy and Neural Models.

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