ADME: In Vitro-In Vivo Extrapolation
Author:   Geoffrey T. Tucker (Royal Hallamshire Hospital, Sheffield, England, UK) ,  Amin Rostami-Hodjegan (University of Sheffield, UK)
Publisher:   Taylor & Francis Inc
ISBN:  

9781420077353


Pages:   350
Publication Date:   15 July 2011
Format:   Hardback
Availability:   Awaiting stock   Availability explained


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ADME: In Vitro-In Vivo Extrapolation


Overview

This comprehensive text focuses on the systems approach to simulating and predicting pharmacokinetic behavior (including metabolism-based drug-drug interactions), in patient populations using demographic, physiological, and genetic information, as well as input from in vitro studies of drug absorption and disposition. ADME emphasizes the use of direct experimental in vitro data obtained from human material (microsomes, cells, tissue slices, recombinant proteins) supported with prediction of relevant parameters from physicochemical properties. Key features include:

Full Product Details

Author:   Geoffrey T. Tucker (Royal Hallamshire Hospital, Sheffield, England, UK) ,  Amin Rostami-Hodjegan (University of Sheffield, UK)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
ISBN:  

9781420077353


ISBN 10:   142007735
Pages:   350
Publication Date:   15 July 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Unknown
Availability:   Awaiting stock   Availability explained

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