Overview

 After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy. 

Full Product Details

Author:   Walter Doerfler ,  Petra Böhm
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of hardcover 1st ed. 2004
Volume:   273
Weight:   0.642kg
ISBN:  

9783642057151

ISBN 10:   3642057152
Pages:   368
Publication Date:   09 December 2010
Audience:   Professional and scholarly ,  Professional and scholarly ,  General/trade ,  Professional & Vocational ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

List of Contents.- 1 Immune System.- Evasion of the Immune System by Adenoviruses.- Immune Evasion by Adenovirus E3 Proteins: Exploitation of Intracellular Trafficking Pathways.- The Coxsackie-Adenovirus Receptor—A New Receptor in the Immunoglobulin Family Involved in Cell Adhesion.- Mechanisms of E3 Modulation of Immune and Inflammatory Responses.- 2 Oncogenesis.- Modulation of Oncogenic Transformation by the Human Adenovirus E1A C-Terminal Region.- Cell Transformation by Human Adenoviruses.- Tumorigenesis by Adenovirus Type 12 in Newborn Syrian Hamsters.- E1A-Based Determinants of Oncogenicity in Human Adenovirus Groups A and C.- 3 Gene Therapy.- Replicating Adenoviruses in Cancer Therapy.- Adenovirus Vectors: Biology, Design, and Production.

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