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OverviewAcute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies. Full Product DetailsAuthor: Lynn M. Schnapp , Carol Feghali-BostwickPublisher: Birkhauser Verlag AG Imprint: Birkhauser Verlag AG Edition: 1st ed. 2017 Dimensions: Width: 15.50cm , Height: 1.30cm , Length: 23.50cm Weight: 4.203kg ISBN: 9783319465258ISBN 10: 3319465252 Pages: 185 Publication Date: 14 November 2016 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsMethods to Study Lung Injury and Repair.- Mouse Models of Acute Lung Injury.- Transgenic Animal Models in Lung Research.- Fundamental Methods for Analysis of Acute Lung Injury in Mice.- Invasive Measurement of Pulmonary Function in Mice.- Analysis of Epithelial Injury and Repair.- Flow Cytometric Evaluation of Acute Lung Injury and Repair.- Lung Imaging in Animal Models.- Genetic and Genomic Approaches to Acute Lung Injury.- MicroRNA Analysis in Acute Lung Injury.ReviewsBasic scientists and clinician investigators with an interest in ARDS are an appropriate audience for this work, which features contributions from clinicians and basic scientists in pulmonary and critical care from academic institutions ... . This is an excellent introduction to work in an area of great interest to intensivists. Investigators needing to understand approaches to an important clinical problem and clinicians needing a better understanding of relevant experimental methods will enjoy and benefit from this book. (David J. Dries, Doody's Book Reviews, January, 2017) Author InformationLynn M. Schnapp, MD Pulmonary, Critical Care, Allergy and Sleep Medicine Medical University of South Carolina Charleston, SC, USA Carol Feghali-Bostwick, PhD Rheumatology and Immunology Medical University of South Carolina Charleston, SC, USA Tab Content 6Author Website:Countries AvailableAll regions |