Overview

Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules: * Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.* Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.

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9780471423652

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Reviews

...a useful book for anyone interested in the measurement of physiochemical parameters that relate to drug permeability. (Journal of Medicinal Chemistry, Vol. 47, No. 7) ...useful compilations of data...of use to those working in the agrochemical and environmental industries... (Chemistry & Industry, 19 January 2004)

...a useful book for anyone interested in the measurement of physiochemical parameters that relate to drug permeability. (Journal of Medicinal Chemistry, Vol. 47, No. 7) ...useful compilations of data...of use to those working in the agrochemical and environmental industries... (Chemistry & Industry, 19 January 2004)

Author Information

Alex Avdeef, PhD, is CEO and CSO of pION Inc., and has over thirty years of experience in chemical instrumentation and software development. He is an internationally know authority on solution chemistry and is the author of an extensive list of publications.

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