Overview

The aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS. In particular, the aims are: (1) to provide an introduction to the key biological processes involved in the pathophysiology of MetS; (2) through the use of specific examples, provide an introduction to the latest technologies that use a systems biology approach to study MetS; and (3) to give an overview of the mathematical modeling approaches for studying MetS. The clearly written chapters by leading experts in the field provides detailed descriptions crucial for the unique position of this book and its focus on the application of systems biology to tackle specific pathophysiologically relevant aspects of MetS and provides a valuable practical guide to this research community.  

Full Product Details

Author:   Matej Orešič ,  Antonio Vidal-Puig
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2014
Dimensions:   Width: 15.50cm , Height: 2.10cm , Length: 23.50cm
Weight:   6.088kg
ISBN:  

9783319347196

ISBN 10:   3319347195
Pages:   384
Publication Date:   23 August 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

The metabolic syndrome and its complex pathophysiology.- Systems biology in human health and disease.- The liver in metabolic syndrome.- Role of adipose tissue in the pathogenesis and treatment of metabolic syndrome.- The beta cell in metabolic syndrome.- The skeletal muscle in metabolic syndrome.- The central nervous system in metabolic syndrome.- Lipid metabolism in metabolic syndrome.- Gut microbiota in metabolic syndrome.- Proteomics in the systems-level study of the metabolic syndrome.- Metabolomics in the systems-level study of the metabolic syndrome.- Fluxomics.- In vitro colon model to study metabolic syndrome.- Genome-scale modeling of tissue and cancer metabolism.- Modeling of lipid membranes and lipoproteins.- Computational statistics approaches to study metabolic syndrome.- Towards modeling of metabolic syndrome: Tissue crosstalk in lipid spillover.

Reviews

Author Information

Tab Content 6

Author Website:  

Countries Available

All regions