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Author:   Seth Joel Corey ,  Marek Kimmel ,  Joshua N. Leonard
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2014 ed.
Volume:   844
Dimensions:   Width: 15.50cm , Height: 2.40cm , Length: 23.50cm
Weight:   0.787kg
ISBN:  

9781493920945

ISBN 10:   1493920944
Pages:   403
Publication Date:   06 December 2014
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Part I: Basic Components.- Systems Hematology:  An Introduction.- Quantification and Modeling of Stem Cell - Niche Interaction.- Angiogenesis: A Systems Biology View of Blood Vessel Remodeling.- Erythropoiesis: From Molecular Pathways to System Properties.- Systems Biology of Megakaryocytes.- Systems Biology of Platelet-Vessel Wall Interactions.- Systems Approach to Phagoycte Production and Activation: Neutrophils and Monocytes.- Part II: Physiological Processes.- Stochasticity and Determinism in Models of Hematopoiesis.- Systems Analysis of High–Throughput Data.- Developing a Systems-Based Understanding of Hematopoietic Stem Cell Cycle Control.- A Systems Biology Approach to Iron Metabolism.- Innate Immunity in Disease - Insights from Mathematical Modeling and Analysis.- Modeling Biomolecular Site Dynamics in Immunoreceptor Signaling Systems.- Structure and Function of Platelet Receptors Initiating Blood Clotting.- Part III: Clinical Applications.- Understanding and Treating Cytopenia through Mathematical Modeling.- Drug Resistance.- Etiology and Treatment of Hematological Neoplasms: Stochastic Mathematical Models.- Assessing Hematopoietic (Stem-) Cell Behavior during Regenerative Pressure.- Engineered Cell-Based Therapies: A Vanguard of Design-Driven Medicine.- Part IV: Epilogue.- A Systems Approach to Blood Disorders.- Index.

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