3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening
Author:   William S. Kisaalita (University of Georgia, Athens, USA)
Publisher:   Taylor & Francis Ltd
ISBN:  

9781138112025


Pages:   404
Publication Date:   13 June 2017
Format:   Paperback
Availability:   In Print   Availability explained
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3D Cell-Based Biosensors in Drug Discovery Programs: Microtissue Engineering for High Throughput Screening


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Author:   William S. Kisaalita (University of Georgia, Athens, USA)
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Weight:   0.750kg
ISBN:  

9781138112025


ISBN 10:   113811202
Pages:   404
Publication Date:   13 June 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Introduction. Biosensors and Bioassays. Target-Driven Drug Discovery. 3D versus 2D Cultures. Comparative Genomics and Proteomics. Comparative Structure and Function. Emerging Design Principles. Chemical Microenvironmental Factors. Spatial and Temporal Microenvironmental Factors. Material Physical Property and Force Microenvironmental Factors. Proteomics as a Promising Tool in the Search for 3D Biomarkers. Readout Present and Near Future. Ready-to-Use Commercial 3D Plates. Technology Deployment Challenges and Opportunities. Challenges to Adopting 3D Cultures in HTS Programs. Cases for 3D Cultures in Drug Discovery. Ideal Case Study Design. Appendices. Index.

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Author Information

William S. Kisaalita, PhD is professor and former coordinator of graduate engineering programs at the University of Georgia, where he also directs the Cellular Bioengineering Laboratory. The main research focus of his laboratory is cell-surface interactions with applications in cell-based biosensing in drug discovery. He has published more than 80 peer reviewed and trade press papers and made more than 100 poster and podium presentations. He has received numerous instructional awards including membership in the University of Georgia Teaching Academy. He is a member of ACS, AAAS, ASEE, and SBS. Dr. Kisaalita serves on the editorial boards of The Open Biotechnology Journal and The Journal of Community Engagement and Scholarship.

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