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Author:   Christopher J Schofield (University of Oxford, UK) ,  Robert Hausinger (Michigan State University, USA) ,  C. David Garner ,  J. Martin Bollinger
Publisher:   Royal Society of Chemistry
Imprint:   Royal Society of Chemistry
Volume:   Volume 3
Dimensions:   Width: 15.60cm , Height: 3.30cm , Length: 23.40cm
Weight:   0.892kg
ISBN:  

9781849739504

ISBN 10:   1849739501
Pages:   532
Publication Date:   06 May 2015
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Biochemical Diversity of 2-Oxoglutarate Dependent Oxygenases; Introduction to Structural Studies on 2-Oxoglutarate Dependent Oxygenases and Related Enzymes; Mechanisms of 2-Oxoglutarate-Dependent Oxygenases; Synthetic Models of 2-Oxoglutarate-Dependent Oxygenases; Collagen Hydroxylases; The Role of 2-Oxoglutarate-Dependent Oxygenases in Hypoxia Sensing; JmjC Lysine Demethylases; AlkB and its Homologues—DNA Repair and Beyond; RNA Demethylation by FTO and ALKBH5; Role of ALKBH8 in the Synthesis of Wobble Uridine Modifications in tRNA; The TET/JBP Family of Nucleic Acid Base-Modifying 2-Oxoglutarate and Iron-Dependent Dioxygenases; 2-Oxoglutarate-Dependent Hydroxylases Involved in DNA Base J (β-D-glucopyranosyloxymethyluracil) Synthesis; Dioxygenases of Carnitine Biosynthesis: 6-N-Trimethyllysine and γ-Butyrobetaine Hydroxylases; Phytanoyl-CoA Hydroxylase: a 2-Oxoglutarate Dependent Dioxygenase Crucial for Fatty Acid Alpha-Oxidation in Humans; Role of 2-Oxoglutarate Dependent Oxygenases in Flavonoid Metabolism; Gibberellin Metabolism; 2-Oxoglutarate Dependent Oxygenases of Cephalosporin Synthesis; Recent Advances in the Structural and Mechanistic Biology of Non-Heme Fe(II), 2-Oxoglutarate, and O2 Dependent Halogenases; Isopenicillin N Synthase; 1-Aminocyclopropane-1-Carboxylic Acid Oxidase; 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase: 2-Oxo Acid-Dependent Oxygenases of Importance to Agriculture and Medicine

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