Overview

In this book, the author has given a comprehensive description of 101 medical autopsy cases (48 adult and 53 pediatric) with their complete clinical and pathological details. Each case is unique and has been discussed in a simple, practical, straightforward, but comprehensive manner. Comprehensive compilation of 101 medical autopsy cases (48 adult and 53 pediatric - children, infants, neonates, stillbirths and terminated fetuses) in a case based manner. First book in the world literature to have compiled medical autopsy cases with complete clinical and pathological details, and agallery of gross and microscopic pictures with review of literature. The cases have been grouped in the following order: hematologic disorders, malignancies, infections, hepatobiliary and pancreatic disorders, cardiovascular system, systemic vasculitides, primary renal mucormycosis, histiocytosis, primary immunodeficiency, infantile nephrotic syndromes, congenital heart disease, storage disorder and pediatric renal cystic disease (developmental/genetic/syndromes). Introduction to medical autopsy, systemic vasculitides, tubercular meningitis and pediatric renal cystic diseases are added for better understanding. Each autopsy case is a complete journey of the patient/deceased and has been concisely discussed under the following headings: title, highlights of the case, clinical details, investigations, clinical diagnosis, complete histopathological or autopsy findings with a gallery of gross and microscopic photographs (3,000 plus), final autopsy diagnosis, review of literature, commentary index case, take home message and suggested reading or references. This book will be a great teaching material for the pathologists, medical physicians, pediatricians, neonatologists, obstetricians, radiologists along with undergraduates/postgraduates students.

Full Product Details

Author:   Nandita Bharadwaj Kakkar
Publisher:   Jaypee Brothers Medical Publishers
Imprint:   Jaypee Brothers Medical Publishers
Weight:   2.540kg
ISBN:  

9789352706129

ISBN 10:   9352706129
Pages:   798
Publication Date:   28 February 2019
Audience:   College/higher education ,  Tertiary & Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Introduction Medical Autopsy: The Strongest Teaching Tool in Medicine Section 1: Hematological Disorders-Adult Cases Case 1: Mantle Cell Lymphoma, Presenting with Florid Cutaneous Lesions, with Common Variant Morphology in the Nodal/Extranodal Sites and Blastoid Morphology in the Peripheral Blood:PM 25983 Case 2: Primary Myelofibrosis, Cellular Phase with Formation of Sclerosing Extramedullary Hematopoietic Tumors: PM 27873 Case 3: Primary Myelofibrosis, Cellular Phase with Extensive Extramedullary Hematopoiesis and Transformation into Acute Leukemia: PM 23618 Case 4: Hepatosplenic T-cell Lymphoma: PM 23096 Case 5: Acute Promyelocytic Leukemia with Early Death due to Disseminated Intravascular Coagulation and Right Temporal Lobe Hemorrhage: PM 26880 Case 6: Acute Promyelocytic Leukemia with Differentiation Syndrome: PM 17959 Case 7: Chronic Lymphatic Leukemia, Post-Bone Marrow Transplantation with Recurrence, Massive Lymphadenopathy and Hemophagocytosis: PM 21710 Case 8: Symptomatic Plasma Cell Myeloma with Primary Systemic Amyloidosis Showing a Predominant Involvement of the Heart and Gastrointestinal Tract: PM 19667 Section 2: Malignancy-Adult Cases Case 9: Microscopic/Occult Testicular Seminoma with Germ Cell Neoplasia in situ and Widespread Nonseminomatous Metastasis in a Young Male: PM 14170 Case 10:Malignant Teratoma, Primary Pulmonary, Containing Yolk Sac tumor, Associated with Hematologic Neoplasia: PM 13633 Case 11:Young Male with Metastasis: Do not Waste Time-Look for the Primary in the Testes: PM 19388 Case 12: Occult, Peripheral, Mucin-secreting Adenocarcinoma of Lung with Florid Meningeal Carcinomatosis along with Thrombotic Microangiopathy and Disseminated Intravascular Coagulation, Leading to Bilateral Renal Infarction: PM 26226 Case 13: Young Male with Occult, Diffuse Type, Mucin-secreting Adenocarcinoma of the Stomach with Extensive Lymphangitic Carcinomatosis, Presenting with Deep Vein Thrombosis and Pulmonary Embolism: PM 21829 Section 3: Infections-Adult Cases Case 14: Amebic Ileocolitis, Perforation and Liver Abscess: PM 18836 Case 15: Cerebral Toxoplasmosis in a Human Immunodeficiency Virus Positive Patient: PM 19210 Case 16: Pulmonary Hyalinizing Granuloma with Recent Onset Cryptococcal Meningoencephalitis in an Immunocompetent Male: PM 21122 Case 17: Leptospirosis with Multiorgan Involvement: PM 22793 Case 18: Silicotuberculosis: PM 26075 Case 19: Rabies Meningoencephalitis, Post-Pet Dog Bite: PM 27786 Section 4: Hepatobiliary and Pancreatic Disorders-Adult Cases Case 20: Extrahepatic Portal Venous Obstruction due to Cavernomatous Transformation of Portal Vein and Portal Cavernoma Cholangiopathy: PM 22260 Case 21: Chronic Budd-Chiari Syndrome with Mesoatrial Shunt, Venocentric Cirrhosis, Hepatocellular Carcinoma Infiltrating into the Hepatic Duct Causing Obstruction and Hemobilia: PM 27800 Case 22: Acute on Chronic Pancreatitis Leading to Portal Vein Pyemia, with Multiple Liver Abscesses and Life-threatening Sepsis Shock: PM 25975 Case 23: Lipomatous Pseudohypertrophy of the Pancreas with Polyglandular Autoimmune Syndrome Type II and Inflammatory Myopathy: PM 22590 Case 24: Young Male with Early Onset Micronodular Cirrhosis due to Synergistic Hepatotoxic Effect of Alcohol and Hepatitis C Virus Infection along with Cryoglobulinemic Vasculitis: PM 27791 Case 25: Diffuse Hepatocellular Carcinoma Arising in a Setting of Mixed Nodular Cirrhosis, Hepatitis C Virus and Alcohol Related: PM 26695 Case 26:Acute Liver Failure and Encephalopathy in a Case of Dengue Shock Syndrome: PM 25035 Case 27: Postpartum, Hyperacute, Fulminant Hepatic Failure due to Hepatitis E Virus: PM 26595 Case 28: Sporadic, Hepatitis E-related Massive Hepatic Necrosis in a Young Female: PM 26254 Case 29: A Classical Case of Wilson's Disease with Hepatic and Neuropsychiatric Manifestations: PM 26195 Section 5: Cardiovascular System-Adult Cases Case 30: Silent Healed Myocardial Infarction and its Complications-Infarct Expansion, Mural Thrombosis, Aneurysm Formation, Extensive Arterial Embolization, Deep Vein Thrombosis and Subsequent Fatal Venous Thromboembolism: PM 21817 Case 31: Coexistence of Acute-on-Chronic Rheumatic Heart Disease and Acute Poststreptococcal Glomerulonephritis: PM 21119 Case 32: A Classical Case of Marfan Syndrome with Aortic Root Dilatation, Aneurysm of the Ascending Aorta and Acute Aortic Dissection: PM 22554 Case 33: Adult Tetralogy of Fallot with Tricuspid Valve Infective Endocarditis and Thromboembolic Botryomycotic Cerebral Abscess: PM 26941 Case 34: Cocaine-induced Vasculopathy Leading to Cardiomyopathy, Renal Infarcts, Gangrene of Digits with Autoamputation: PM 23445 Case 35: Aftermath of Hypertension in a Middle-aged Male-Intraparenchymal Brain Hemorrhage, Pontine and Thalamic: PM 26485 Section 6: Systemic Vasculitides-Adult and Pediatric Cases Systemic Vasculitides-Introduction Small Vessel Vasculitides Case 36: Renal Limited Microscopic Polyangiitis: PM 13127 Case 37: Microscopic Polyangiitis, ANCA Negative, with Florid Glomerulitis and Granulomatous Glomerulonephritis: PM 15649 Case 38: Microscopic Polyangiitis in a Child: PM 16450 Case 39: Microscopic Polyangiitis, ANCA Negative, Clinically Mimicking Granulomatosis with Polyangiitis (Wegener's Granulomatosis) and Presenting with a Breast Mass: PM 18473 Case 40: Microscopic Polyangiitis-Chronic Phase: PM 18987 Case 41: Microscopic Polyangiitis with Acute Vasculitis of Small, Medium and Large-sized Arteries: PM 20415 Case 42: p-ANCA Positive Classic Polyarteritis Nodosa: PM 24277 Case 43: Takayasu's Aortoarteritis, Pulmonary Hypertension, and Pulmonary Capillary Hemangiomatosis: PM 14993 Case 44: Takayasu Aortoarteritis, Presenting with Pulmonary Arterial Hypertension Secondary to Extensive Involvement of Right Pulmonary Artery: PM 25988 Case 45: Granulomatosis with Polyangiitis (Wegener's Granulomatosis) with Left Foot Gangrene and Right Hemiplegia: PM 14106 Case 46: Granulomatosis with Polyangiitis-Wegener's Granulomatosis, Presenting as an Anterior Mediastinal Mass: PM 18613 Case 47: Granulomatosis with Polyangiitis, i.e Wegener's with Multiple Pulmonary Nodules and Total Splenic Necrosis: PM 21594 Case 48: c-ANCA Positive, Nonreactive, Disseminated Tuberculosis with Pulmonary and Mesenteric Vasculitis: PM 14513 Section 7: Primary Renal Mucormycosis-Adult and Pediatric Cases Case 49: Isolated Bilateral Renal Mucormycosis with Contiguous Spread to the Adrenals, Mesentery, Pancreas and Colon in an Apparently Immunocompetent Adult: PM 27250 Case 50: Primary Bilateral Renal Mucormycosis in an Apparently Immunocompetent Child: PM 22863 Section 8: Histiocytosis-Pediatric and Adult Cases Case 51: Primary/Familial Hemophagocytic Lymphohistiocytosis with Extensive Involvement of the Brain: PM 20788 Case 52: Langerhans Cell Histiocytosis Presenting as an Anterior Mediastinal Mass: PM 21476 Case 53: Macrophage Activation Syndrome-A Fatal Complication of Systemic Onset Juvenile Idiopathic Arthritis: PM 26202 Case 54: Epstein-Barr Virus-associated Secondary Hemophagocytic Lymphohistiocytosis- A Rare Complication: PM 21703 Section 9: Primary Immunodeficiency-Pediatric Cases Case 55: Disseminated Bacillus Calmette-Guerin Infection in a Case of Severe Combined Immunodeficiency: PM 22931 Case 56: Chronic Granulomatous Disease of Childhood: PM 24170 Case 57: Disseminated Nonreactive Tuberculosis, PCR-Proven Dual Positivity for Mycobacterium Tuberculosis and Abscessus ? Mendelian Susceptibility to Mycobacterial Disease: PM 25174 Section 10: Infantile Nephrotic Syndrome Case 58: Congenital Nephrotic Syndrome of the Finnish Type: PM 23777 Case 59: Infantile Nephrotic Syndrome-Diffuse Mesangial Sclerosis in a 10-Month-Old Male Child: PM 26462 Section 11: Infections-Pediatric Cases Case 60: Disseminated Congenital Cytomegalovirus Infection with Islet Cell Hyperplasia as the Cause of Persistent Hypoglycemia in a Neonate: PM 23822 Case 61: Congenital Tuberculosis: An Underdiagnosed Entity: PM 24753 Case 62: Disseminated Cryptococcomas Mimicking Disseminated Malignancy, with Hepatic Dysfunction as the Initial Manifestation, in an Immunocompetent Child: PM 25744 Introduction to Tubercular Meningitis Case 63: Catastrophic Posterior Circulation Tubercular Arteritis with Infarcts and Cortical Venous Thrombosis-A Rare Co-existence: PM 26344 Case 64: Child with Disseminated Miliary Tuberculosis, Tubercular Meningitis with Extensive Arteritis, Infarction and Ischemic Hepatitis: PM 25901 Case 65: Disseminated Cryptococcal Infection in an HIV-positive Child: PM 23563 Section 12: Cardiovascular System-Pediatric Case Case 66: Transposition of Great Arteries: PM 24027 Section 13: Hematological Disorders-Pediatric Cases Case 67: Child with Acute Lymphoblastic Leukemia on Induction Therapy with Febrile Neutropenia and Disseminated Aspergillus Infection: PM 25927 Case 68: Myeloid Sarcoma of Lacrimal Sac as the First Manifestation of AML-M1 with Acute Diffuse Colorectal Neutropenic Colitis in a Child: PM 23395 576 Section 14: Storage Disorder Case 69: Niemann-Pick Type B Presenting with Massive Splenohepatomegaly and Hypertensive Crisis in a 12-year-old Child: PM 27096 Section 15: Pediatric Renal Cystic Disease (Developmental/Genetic/Syndromes) Pediatric Cystic Disease (Developmental/Genetic) of Kidney-Introduction Section 15A: Renal Dysplasia Case 70: Recurrent Bilateral Multicystic Dysplastic Kidneys, Consistent with Hereditary Renal Adysplasia: PM 20505 Case 71: Symmetrically Enlarged, Solid Dysplastic Kidneys with Intrauterine Growth Retardation: PM 24340 Case 72: Multicystic Dysplastic Kidneys with Dilated Ureters and Hypertrophied Urinary Bladder Leading to Obstructed Labor and Uterine Rupture: PM 26207 Case 73-74: Renal Hypodysplasia: PM 19521, PM 25711 619 Nandita Bharadwaj Kakkar Case 75: Bilateral Renal Agenesis: PM 24019 Case 76-80: Unilateral Renal Malformation: PM 22428, PM 22393, PM 26428, PM 26291, PM 26824 Case 81: Segmental Renal Dysplasia with Duplex Kidney and Ureterocele: PM 19965 Section 15B: Posterior Urethral Valve Case 82-83: Posterior Urethral Valve Leading to Congenital Hydroureteronephrosis and Hypertrophied Urinary Bladder: PM 18485, PM 26118 Section 15C: Renal Hypoplasia Case 84: Neonate with Bilateral Simple Renal Hypoplasia, Lung Hypoplasia and Hydrocephalous: PM 27245 Case 85: Bilateral Simple Renal Hypoplasia, Cystic Periventricular Leukomalacia with Hydrocephalus ex vacuo in Surviving Twin, after death of Monochorionic Co-twin: PM 25677 Case 86: Segmental Hypoplasia (Ask-Upmark Kidney): S-14525/2008 Section 15D: Genetic Disorders Case 87: A Classical Case of Autosomal Recessive Polycystic Kidney Disease: PM 22879 Case 88: Autosomal Dominant Polycystic Kidney Disease with Cyst Infection: PM 22828 Section 15E: Glomerulocystic Kidney Disease Case 89: Co-existing Glomerulocystic Kidney Disease and Renal Tubular Dysgenesis with Late Onset Oligohydramnios and Renal Failure at D2 of Life: PM 28154 Case 90: Glomerulocystic Kidney Associated with Posterior Urethral Valve- A Rare Association: PM 28255 Section 15F: Syndromes Case 91-92: Meckel-Gruber Syndrome: PM 20070, PM 26190 Case 93-94: Prune Belly Syndrome Leading to a Markedly Distended Urinary Bladder and Hydroureteronephrosis: PM 23424, PM 25509 Case 95: Sirenomelia with Bilateral Renal Agenesis and Multiple Other Malformations: PM 27025 Section 16: Liver Disorders-Pediatric Cases Case 96: Coexistence of Duarte 2 Variant of Galactosemia with Niemann-Pick Disease Type B, in an Infant: PM 23108 Case 97: A Classical Case of Galactosemia: PM 23869 Case 98: Galactosemia, Double Heterozygous for N314D and Q188R Mutations, with Micronodular Cirrhosis and Absence of Steatosis: PM 25342 Case 99: A Case of Galactosemia, Double Heterozygous for Q188R and E308K Mutations with Early Neonatal Acute Liver Failure: PM 25552 Case 100: Neonate with Hemolytic Disease of Newborn (Due to Rh Isoimmunization-for both Rh-D Antigen and Rh-C Antigen), Conjugated Hyperbilirubinemia, and Associated Nonsyndromic Paucity of Intrahepatic Bile Ducts: PM 27937 Case 101: Indian Childhood Cirrhosis: PM 24527 Abbreviations Index

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