Surface-Enhanced Raman Spectroscopy: Bioanalytical, Biomolecular and Medical Applications

Author:   Marek Prochazka
Publisher:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2016
ISBN:  

9783319795652


Pages:   221
Publication Date:   30 March 2019
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Surface-Enhanced Raman Spectroscopy: Bioanalytical, Biomolecular and Medical Applications


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Overview

This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.

Full Product Details

Author:   Marek Prochazka
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2016
Weight:   0.454kg
ISBN:  

9783319795652


ISBN 10:   3319795651
Pages:   221
Publication Date:   30 March 2019
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Introduction.- Basics of Raman scattering (RS) spectroscopy.- Basics of surface-enhanced Raman scattering (SERS).- Bioanalytical SERS applications.- Biomolecular SERS applications.- SERS investigations of cells, viruses and microorganisms.- Medical applications of SERS.- Conclusions and outlook.

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