Overview

The strong trend in the Biological Sciences towards a quantitative characterization of processes has promoted an increased use of thermo­ dynamic reasoning. This development arises not only from the well­ known power of thermodynamics to predict the direction of chemical change, but also from the realization that knowledge of quantitative thermodynamic parameters provides a deeper understanding of many biochemical problems. The present treatise is concerned primarily with building up a reliable data base, particularly ofbiothermodynamic and related quantities, such as partial specific volumes and compressibilities, which will help scientists in basic and applied research to choose correct data in a special field that may not be their own. Most chapters reflect this emphasis on data provision. However, it was also felt that the expert user deserved information on the basic methodology of data acquisition and on the criteria of data selection. Therefore all tables are preceded by a critical evaluation of the techniques as well as a survey of the pertinent studies in the corresponding areas. The surveys are usually self-consistent and provide references to further sources of data that are important but not covered in the present volume. The reader will realize that in different chapters, different symbols have be~n used for the same properties. This unfortunate situation is particularly obvious in those chapters where partial specific or molar quantities had to be introduced; however, it also occurs in those contributions concerning phase changes of macromolecules.

Full Product Details

Author:   Hans-Jürgen Hinz
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1986
Dimensions:   Width: 17.00cm , Height: 2.40cm , Length: 24.40cm
Weight:   0.814kg
ISBN:  

9783642711169

ISBN 10:   3642711162
Pages:   456
Publication Date:   17 November 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Section I Introduction.- 1 Present and Future Uses and a Bit of History.- Section II Nonreacting Systems.- 2 Partial Molar Volumes of Biochemical Model Compounds in Aqueous Solution.- 3 Specific Volumes of Biological Macromolecules and Some Other Molecules of Biological Interest.- 4 Partial Molar Compressibilities of Organic Solutes in Water.- 5 Heat Capacities of Biological Macromolecules.- 6 Thermodynamics of Carbohydrate Monomers and Polymers in Aqueous Solution.- Section III Interactions in Solution.- 7 Thermodynamic Data for Protein-Ligand Interaction.- 8 Thermodynamics of Protein-Protein Association.- 9 Hemoglobin.- Section IV Solution Processes.- 10 Gas-Liquid and Solid-Liquid Phase Equilibria in Binary Aqueous Systems of Nonelectrolytes.- 11 Thermodynamic Parameters of Biopolymer-Water Systems.- Section V Phase Changes.- 12 The Formation of Micelles.- 13 Unfolding of Proteins.- 14 The Thermodynamics of Conformation Transitions in Polynucleotides.- 15 Methods for Obtaining Thermodynamic Data on Oligonucleotide Transitions.- Section VI Enzyme Catalyzed Processes.- 16 Thermodynamic of Enzymatic Reactions.

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