Overview

Bestselling author of The Good Nurse, Charles Graeber details the discovery of cancer's secret weakness and how a new generation of scientists finally cracked the code on how the human immune system can fight-and beat-the disease. One hundred years ago, physicians marveled at what appeared to be patients with bacterial infections spontaneously being cured of deadly tumors. What was a miraculous mystery then is now hard scientific fact: immunotherapy is the cutting edge of cancer treatment, and a crucial breakthrough in the race to find the ultimate cure. In The Breakthrough, journalist Charles Graeber expertly traces the fascinating history of immuno-oncology and guides readers through the revolutionary scientific research bringing immunotherapy into the twenty-first century. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step-harnessing the wealth of new information into modern and more effective patient therapies-is already well underway. The Breakthrough is the first book to address the game-changing science of cancer treatment through immunotherapy. It is the incredible true story of the race to find a cure, a dispatch from the life-changing world of oncological science, and a brave new chapter in our relationship with cancer.

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9781549176487

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Reviews

Training the body's immune system to fight disease now offers the most promising developments in the effort to battle cancer. Graeber recounts the treatment's nineteenth-century origins and provides a panoramic view of the work being done today to make it effective. -- New York Times Book Review In Mr. Graeber's hands, the evolution of immuno-oncology is both captivating and heartbreaking. We are immersed in the stories of the brave, desperate patients who try emerging therapies...We can't fail to see ourselves, our friends, and our families in these stories. -- Wall Street Journal Deft, detailed...fascinating. From the once-discredited pioneer William Coley to immunologist and Nobel laureate James P. Allison, (the characters) form a brilliant, driven, admirably stubborn group that Graeber brings vividly to life. -- Nature Crisp and suspenseful...the perfect backstory for this year's Nobel Prize in Medicine. -- BBC (London)

Crisp and suspenseful...the perfect backstory for this year's Nobel Prize in Medicine. -- BBC (London) Deft, detailed...fascinating. From the once-discredited pioneer William Coley to immunologist and Nobel laureate James P. Allison, (the characters) form a brilliant, driven, admirably stubborn group that Graeber brings vividly to life. -- Nature In Mr. Graeber's hands, the evolution of immuno-oncology is both captivating and heartbreaking. We are immersed in the stories of the brave, desperate patients who try emerging therapies...We can't fail to see ourselves, our friends, and our families in these stories. -- Wall Street Journal Training the body's immune system to fight disease now offers the most promising developments in the effort to battle cancer. Graeber recounts the treatment's nineteenth-century origins and provides a panoramic view of the work being done today to make it effective. -- New York Times Book Review

Author Information

Charles Graeber has written for Wired, GQ, the New Yorker, New York, Outside, Bloomberg Businessweek, and the New York Times, among other publications. His work has received numerous awards, including the 2011 Ed Cunningham Award for outstanding international journalism from the Overseas Press Club and a New York Press Club Prize. Born in Iowa, he lives in Nantucket, Massachusetts, and Brooklyn, New York. Will Collyer, an AudioFile Earphones Award-winning narrator, is a film, television, and stage actor. He has starred in television shows such as Melrose Place, Charmed, CSI: Miami, and Boston Public, as well as numerous films and plays. He holds a BA in theater arts from the UCLA School of Theater, Film, and Television.

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