Overview

Detailing the latest developments in the basic science and emerging therapies for Alzheimer's and Parkinson's Diseases, this book brings together the proceedings of Alzheimer's and Parkinson's Diseases: New Perspectives, the Sixth International Conference on Alzheimer's Disease and Parkinson's Disease, held in Seville, Spain on 8-12 May 2003. Areas discussed include: * mechanisms of degeneration of Parkinson's Disease * the interrelationships between gait and cognitive function * advances in gene transfer and pharmacological regulation of protein aggregation in the treatment of Alzheimer's and Parkinson's Diseases * Alzheimer pathology and ER stress * stem cell strategies for Alzheimer's Disease. With cutting-edge, expert contributions from leaders in the field, this is undoubtedly an important text for neurologists, neuroscientists and researchers working with Alzheimer's and Parkinson's Diseases.

Full Product Details

Author:   Israel Hanin ,  Ramon Cacabelos (Santa Maria de Babio, La Coruna, Spain) ,  Abraham Fisher
Publisher:   Taylor & Francis Ltd
Imprint:   CRC Press
Dimensions:   Width: 18.90cm , Height: 2.80cm , Length: 24.60cm
Weight:   1.133kg
ISBN:  

9781841843209

ISBN 10:   1841843202
Pages:   406
Publication Date:   03 June 2005
Audience:   General/trade ,  College/higher education ,  Professional and scholarly ,  General ,  Tertiary & Higher Education
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Mechanisms of Degeneration of Parkinson's Disease. Underlying Biochemical and Molecular Mechanisms of Dyskinesia. Molecular Neuropathology of Parkinsonism. Familial PD Mutations Affect the Ability of Catecholaminergic Neurons to Withstand Proteasome Inhibition. AChE, Cholinergic Signalling, and Parkinson's Disease. Bone Marrow Stem Cells: Possible Source for Cell Therapy in Parkinson's Disease. Insulin-Like Growth Factor I (IGF-I) and Intracellular Signal Transduction Pathways in Aging and Dementia. The Interrelationships Between Gait and Cognitive Function. Advances in Gene Transfer and Pharmacological Regulation of Protein Aggregation in the Treatment of Alzheimer's and Parkinson's Diseases. Two Parent Proteins That Display Similar Anti-apoptotic Phenotypes But Distinct Responses to 6 - Hydroxydopamine - Induced Toxicity. Functional Genomics and Pharmacogenetics in Alzheimer Disease. The Genetics of Tau and Neurodegenerative Disease. Amyloid Plaques and Neurofibrillary Tangles in a Triple Transgenic Model: Qualitative Similarities With Human Alzheimer's Neuropathology. Apolipoprotein E and Alzheimer's Disease: What Has a Decade Told Us? Comparison of the Effects of ApoE4 on Presynaptic and Cytoskeletal Plasticity Following Environmental Stimulation. Cholesterol and Amyloid ??Cascade: Pathological Implications of Apolipoprotein E in Alzheimer's Disease. Brain Inflammation and Psychogeriatric Disease. Neuroinflammatory Mechanisms are Involved in the Early Steps of the Pathological Cascade in Alzheimer's Disease. Vascular Nitric Oxide: A Key Molecule in Alzheimer's Disease Pathogenesis. Alzheimer Pathology and ER Stress. Molecular Mechanism of Amyloid ??Peptide - Induced Impairment of Neurotransmission and Memory in Relation to Oxidative Stress.Regulating Factors for Microglial Activation: Implication for Alzheimer Disease and Brain Damage.CSF Phosphorylated Tau Protein at Serine 199 is a Useful Diagnostic Biomarker in Alzheimer's Disease and Mild Cognitive Impairment. Stem Cell Strategies for Alzheimer's Disease. Can Mild Cognitive Impairment Predict Alzheimer's Disease? Lack of Effect of Certoparin in P301L Mutant Tau Pathology.Heparin - Derived Oligosaccharides as Potential Therapeutic Agents in Senile Dementia and Stroke. Human Prion Diseases.

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Author Information

Israel Hanin, PhD, is Professor and Chairman, Department of Pharmacology and Experimental Therapeutics, Loyola University Medical Center, Maywood, Illinois, USA Ramon Cacabelos, MD, PhD, DMSci, is President and Chief Executive Officer, EuroEspes, Santa Maria de Babio, La Coruna, Spain. Abraham Fisher, PhD, is Chief Scientists, Israeli Institute for Biological Research, Ness-Ziona, Israel.

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