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OverviewFar from being a direct complication of primary damage to heart muscle, it is now recognised that the pathogenesis of heart failure may rely on a combination of neurohormonal, cellular and molecular factors. An overwhelming number of systems appear to be activated in heart failure and contribute in some way towards structural remodelling. Comprising a comprehensive evaluation of the experimental and clinical data relating oxidative stress and heart failure, this text proposes that oxidative stress may be the common pathway for muscle dysfunction, cellular growth and remodelling, and mytocyte death. Acknowledged experts in the field here present a persuasive argument for raising the profile of oxidative stress as an important, perhaps critical contributor to the adverse consequences of heart failure. This volume should serve as a rich source of supportive data for clinicians and investigators interested in the pathophysiology and treatment of heart failure, and as a platform on which to base further research. Full Product DetailsAuthor: Marrick Kukin (Associate Professor of Medicine, Mount Sinai Medical Center, New York) , Valentin Fuster (Director, Cardiovascular Institute, Mount Sinai Medical Center, New York)Publisher: John Wiley and Sons Ltd Imprint: Wiley-Blackwell Dimensions: Width: 16.30cm , Height: 2.40cm , Length: 23.60cm Weight: 0.680kg ISBN: 9780879937096ISBN 10: 0879937092 Pages: 320 Publication Date: 29 November 2002 Audience: College/higher education , Professional and scholarly , Undergraduate , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Out of stock  The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsThe authors, experts in the field, describe the methods and results of their studies conducted in their own laboratory. Nevertheless, the authors manage to keep the text focused and quite comprehensible for the general clinician... This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development... This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement. Jose C Mendez, MD (Loyola University Stritch School of Medicine) Doodya s Review Service "The authors, experts in the field, describe the methods and results of their studies conducted in their own laboratory. Nevertheless, the authors manage to keep the text focused and quite comprehensible for the general clinician..."This book provides a comprehensive overview of the heart failure syndrome and the evidence of the role of oxidative stress in its development..."This book can be useful for clinicians to further their understanding of the pathogenesis of heart failure and how the different therapeutic pathways may improve mortality and morbidity. Furthermore, for those who are currently pursuing research in this field, the book serves as an excellent reference guide in addition to being a source of ideas and encouragement."Jose C Mendez, MD (Loyola University Stritch School of Medicine)Doody's Review Service Author InformationMarrick Kukin is the editor of Oxidative Stress and Cardiac Failure, published by Wiley. Valentin Fuster is the editor of Oxidative Stress and Cardiac Failure, published by Wiley. Tab Content 6Author Website:Countries AvailableAll regions |
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