Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

Author:   Jesus Giraldo (Universitat Autonoma de Barcelona, Spain) ,  Francisco Ciruela (University of Barcelona, Spain)
Publisher:   Elsevier Science Publishing Co Inc
ISBN:  

9780128179291


Pages:   348
Publication Date:   28 January 2020
Format:   Hardback
Availability:   Manufactured on demand   Availability explained
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Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors


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Overview

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scienti?c importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine ß-synthase, and Oligomerization of Porphobilinogen Synthase.

Full Product Details

Author:   Jesus Giraldo (Universitat Autonoma de Barcelona, Spain) ,  Francisco Ciruela (University of Barcelona, Spain)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Weight:   0.720kg
ISBN:  

9780128179291


ISBN 10:   0128179295
Pages:   348
Publication Date:   28 January 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Fluorescence microscopy methods for the study of protein oligomerization Roberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia 2. Computational prediction and redesign of aberrant protein oligomerization Jaime Santos, Valentín Iglesias and Salvador Ventura 3. Porphobilinogen synthase: An equilibrium of different assemblies in human health Eileen K. Jaffe 4. Prediction and targeting of GPCR oligomer interfaces Carlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira 5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomers Francesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas 6. Exploring functional consequences of GPCR oligomerization requires a different lens Kyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert 7. Continuing challenges in targeting oligomeric GPCR-based drugs Joaquin Botta, Julia Appelhans and Peter J. McCormick 8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati 9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action Faron-Górecka Agata, Kusmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta 10. Oligomerization of G protein-coupled receptors: Still doubted? Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo

Reviews

This is a very important book that covers protein oligomerization in health and disease and provides essential knowledge of the oligomeric protein biology, which is critical to allow pharmacologic interventions in diseases associated with oligomeric protein malfunction. This is a unique book dedicated to fully explaining all about protein oligomerization. --Doody


"""This is a very important book that covers protein oligomerization in health and disease and provides essential knowledge of the oligomeric protein biology, which is critical to allow pharmacologic interventions in diseases associated with oligomeric protein malfunction. This is a unique book dedicated to fully explaining all about protein oligomerization."" --Doody"


Author Information

Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain. Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.

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