Overview

Advanced renal cell carcinoma is resistant to nearly all forms of systematic therapy. For this reason the last decade has seen numerous research groups working on immunotherapeutic strategies. ""Immunotherapy of Renal Cell Carcinoma"" reports the contributions of most of the world's leading research groups to two international conferences on the immunobiology of this illness. 16 chapters divided into experimental and clinical studies provide an overview of immunotherapy in renal cell carcinoma and a discussion of new laboratory approaches to this topic. The scope of subjects ranges from basic studies of oncogenes and MDRI gene expression, experimental metastases, radio-immunoconjugates, TIL-and LAK-cells, monoclonal antibodies to clinical trials with Interferon, Tumour Necrosis Factor and Interleukin-2. This book will be of interest to clinicians and researchers working in the areas of urology, pathology, medical oncology and radiotherapy. For basic scientists it will be a source of information on clinical aspects of this disease; for clinicians it will provide a review of the current achievements of basic research in the field of immunology and immunotherapy of renal cell carcinoma.

Full Product Details

Author:   R.J.A. van Moorselaar ,  Frans M.J. Debruyne ,  Ronald M. Bukowski ,  J. Edson Pontes
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Dimensions:   Width: 15.50cm , Height: 0.80cm , Length: 23.50cm
Weight:   0.255kg
ISBN:  

9783540528357

ISBN 10:   3540528350
Pages:   141
Publication Date:   29 January 1991
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock  
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Table of Contents

Experimental Data.- Considerations in Immunotherapy of Genitourinary Neoplasia.- Murine Renal Cancer (Renca) Model: Background and Preclinical Studies.- Renal Cell Carcinoma: Experimental Metastases.- Oncogenes in Renal Cell Carcinoma.- Molecular Basis and Clinical Relevance of MDR1 Gene Expression in Renal Cell Carcinoma.- Radioimmunoconjugates in Renal Cell Carcinoma.- Interferon and Tumor Necrosis Factor in Renal Cell Carcinoma Model Systems.- Clinical Experience with Biological Response Modifiers in Renal Cell Carcinoma.- Rationale for Immunotherapy in Renal Cell Carcinoma.- Treatment of Renal Cell Carcinoma with Interferon.- Combination Therapy with Interferon in Renal Cell Carcinoma.- Recombinant Interferon Alpha Plus Vinblastine in Metastatic Renal Cell Cancer: Updated Results.- Monotherapy and Combination Therapy with Interferon-?, Interferon-?, and Tumor Necrosis Factor-? in Metastatic Renal Cell Carcinoma.- Treatment of Advanced Renal Cell Carcinoma by Systemic Low-Dose Recombinant Interleukin-2.- Direct Lymphatic Immunotherapy for Metastatic Renal Cell Carcinoma.- Combination Therapy of Renal Cell Carcinoma with Interleukin-2 and Interferon Alpha: The Cleveland Clinic Experience.- Tumor Infiltrating Lymphocytes in Human Renal Cell Carcinoma: Adoptive Immunotherapy and Characterization of Interleukin-2 Expanded Tumor-Infiltrating Lymphocytes.- Active Specific Immunotherapy in Renal Cell Carcinoma: Optimization.

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