Overview

The patient in front of you has new ascites, a creatinine that won't stop climbing, an INR of 2.4 that nobody knows whether to correct, and a 2.8 cm liver lesion that wasn't there six months ago - and the decisions cannot wait until morning rounds. Apply yesterday's hepatology to today's patient and you miss the LR-5 diagnosis, anchor on outdated MELD-Na priorities, dose carvedilol into a hepatorenal spiral, or refer for transplant six months too late. This handbook rebuilds clinical reasoning around the hepatology that exists right now - so you read the imaging, stratify the cirrhosis, dose the antiviral, time the transplant referral, and integrate the systemic therapy with the confidence the case demands. Inside this book: - Decompensation decoded - manage variceal hemorrhage, refractory ascites, hepatic encephalopathy, and hepatorenal syndrome with the protocols that actually move outcomes - MASLD redefined - apply the 2023 nomenclature, stage fibrosis noninvasively, and integrate resmetirom into MASH care - HCC at the bedside - apply LI-RADS to the indeterminate nodule, stage by BCLC, and select between IMbrave150 and HIMALAYA combination immunotherapy - Hepatitis cured and contained - deploy DAAs to SVR in eight weeks, prevent vertical HBV transmission with TDF, and treat hepatitis D with bulevirtide - Cholestasis sharpened - separate PBC from PSC from IgG4-related disease and intervene before fibrosis accelerates - Transplant decisions sequenced - apply MELD 3.0, navigate exception points, and time the referral before the window closes - Pregnancy, pediatrics, and the systemic patient - recognize ICP, AFLP, Fontan-associated liver disease, and the hepatic manifestations adult medicine sends your way For hepatologists, gastroenterologists, hospitalists, internists, transplant teams, advanced practice providers, residents, and fellows caring for patients with liver disease. Buy this handbook and commit to the standard of hepatology care every patient on your service deserves.

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