Overview

Crohn's Disease (CD) is one of the most important chronic inflammatory bowel diseases (IBD) that can affect the whole gastrointestinal tract from mouth to anus and whose inflammation extends through all layers of the gut wall. Treatments normally consist of controlling the symptoms, maintaining remission, and preventing relapse. Despite many years of study, the exact aetiology and pathogenesis of this disorder still remains unclear; however, great advances have been made in the last decades and have provided insights into the complex, multi-factorial processes and mechanisms that can result in chronic intestinal inflammation such as those present in Crohn's Disease. This book will describe etiological factors (host-microbiome interactions, nutrition, immune system, genetic and life-styles), novel and conventional diagnostic tools (magnetic resonance enterography, multidetector contrast-enhanced computed tomography, small bowel magnetic resonance imaging, intestinal ultrasound, endoscopy and histology), complications (musculo-skeletal, and intra-abdominal) along with conventional and novel treatment options (strictureplasty techniques, use of biological agents, probiotic micro-organisms and genetically engineered lactic acid bacteria) for CD and other IBD. This new book is a compilation of topics that have been written by experts from all over the world (Argentina, Australia, Brazil, Chile, France, Hungary, Italy, Spain, United Kingdom and the United States of America) who work in medical, clinical or research settings offering different viewpoints on the most up-to-date information currently available on Crohn's Disease.

Full Product Details

Author:   Jean Guy LeBlanc ,  Alejandra de Moreno de LeBlanc
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Weight:   0.788kg
ISBN:  

9781626185838

ISBN 10:   1626185832
Pages:   352
Publication Date:   19 June 2013
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order  
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Table of Contents

Preface; Current Knowledge in Inflammatory Bowel Diseases Immunopathogenesis; Crohn's Disease within the Hologenome Paradigm; Nutrition & Inflammatory Bowel Disease; Pathogenesis of Crohns Disease: The Role of Lifestyle; Ibd3 Genomic Loci in Crohn's Disease: Immunogenetics of HLA & NKG2D Ligands (MICA) Genes; Diagnostic & Assessment Issues in Crohns Disease; Magnetic Resonance Enterography: Review of the Technique & Assessment of Crohn's Disease: Spectrum of Findings & Disease Activity; Cross-Sectional Imaging of High- & Low-Grade Bowel Obstruction from Crohns Disease using Multidetector CT & MRI, Including Enteroclysis & Enterography Techniques; Musculo-Skeletal Complications of Crohns Disease: Spondylitis, Sacroiliitis & Peripheral Arthritis; Intra-abdominal Complications of Fistulizing Crohns Disease: Spectrum of Cross-Sectional Imaging Findings; A Review of Strictureplasty Techniques in Crohn's Disease: Types, Indications & Comparisons; Biological Agents Therapy in Crohns Disease; Prediction of Response, Dose Intensification & Loss of Response to Anti TNF Therapy in Inflammatory Bowel Diseases; Use of Probiotics in the Treatment of Crohns Disease; Use of Genetically Engineered Lactic Acid Bacteria for the Treatment of Crohns Disease; Index.

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