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Huntingt n dis s (HD) is h r dit ry, n ur d g n r tiv illn ss with physic l, c gnitiv nd m ti n l sympt ms. Huntingt n dis s is c us d by mut ti n in th g n th t m k s th pr t in c ll d huntingtin. In p pl with HD, th C G s qu nc is r p t d t m ny tim s t th b ginning f th g n . Th t c us s c lls t m nuf ctur h rmful pr t in c ll d mut nt huntingtin. Th mut nt huntingtin pr t in c us s c rt in p rts f th br in t di - sp cific lly th c ud t , th put m n nd, s th dis s pr gr ss s, th c r br l c rt x. s th br in c lls di , sympt ms will pp r in ch f th thr c mp n nts (physic l, c gnitiv nd m ti n l). Huntingt n dis s is g n tic dis rd r. Th HD g n is d min nt, which m ns th t ch child f p r nt with HD h s 50% ch nc f inh riting th dis s nd is s id t b t-risk. M l s nd f m l s h v th s m risk f inh riting th dis s . HD ccurs in ll r c s. Sympt ms usu lly pp r b tw n th g s f 35 nd 55, but th dis s c n pp r in y uth (und r 20 y rs - Juv nil HD) r ld r dults (L t ns t HD).Sympt ms f Huntingt n's

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9781090163240

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