Bioisosteres in Medicinal Chemistry

Author:   Nathan Brown (The Institute of Cancer Research, Sutton, UK) ,  Raimund Mannhold (University of Düsseldorf, Ge) ,  Hugo Kubinyi (University of Heidelberg, Germany) ,  Gerd Folkers (Swiss Institute of Technology (ETH), Zürich, Switze)
Publisher:   Wiley-VCH Verlag GmbH
ISBN:  

9783527330157


Pages:   256
Publication Date:   22 August 2012
Format:   Hardback
Availability:   Out of stock   Availability explained
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Bioisosteres in Medicinal Chemistry


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Author:   Nathan Brown (The Institute of Cancer Research, Sutton, UK) ,  Raimund Mannhold (University of Düsseldorf, Ge) ,  Hugo Kubinyi (University of Heidelberg, Germany) ,  Gerd Folkers (Swiss Institute of Technology (ETH), Zürich, Switze)
Publisher:   Wiley-VCH Verlag GmbH
Imprint:   Blackwell Verlag GmbH
Dimensions:   Width: 17.40cm , Height: 1.60cm , Length: 24.60cm
Weight:   0.631kg
ISBN:  

9783527330157


ISBN 10:   3527330151
Pages:   256
Publication Date:   22 August 2012
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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<p> In all, I believe this book is a musthave handbook onbioisosteres. It is highly valuable both as a text book forgraduate students and as a book of reference for the medicinalchemist working in the industry as well as in an academicsetting. (ChemMedChem, 1 July 2013)


In all, I believe this book is a musthave handbook on bioisosteres. It is highly valuable both as a text book for graduate students and as a book of reference for the medicinal chemist working in the industry as well as in an academic setting. ( ChemMedChem , 1 July 2013)


Author Information

Nathan Brown is the Head of the In Silico Medicinal Chemistry group in the Cancer Therapeutics Unit at The Institute of Cancer Research in London (UK). At the ICR, Nathan and his group support our entire drug discovery portfolio together with developing new computational methodologies to enhance our drug design work. Nathan conducted his doctoral research in Sheffield with Professor Peter Willett focusing on evolutionary algorithms and graph theory. After a two-year Marie Curie fellowship in Amsterdam in collaboration with Professor Johann Gasteiger in Erlangen, he joined the Novartis Institutes for BioMedical Research in Basel for a three-year Presidential fellowship in Basel working with Professors Peter Willett and Karl-Heinz Altmann. Nathan?s work has led to the pioneering work on mulitobjective de novo design in addition to a variety of discoveries and method development in bioisosteric identification and replacement, scaffold hopping, molecular descriptors and statistical modelling. Nathan continues to pursue his research in all aspects of in silico medicinal chemistry.

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